Academic Catalog

Biomedical Engineering (4800)

4800:522. Physiological Control Systems. (3 Credits)

Prerequisite: 3100:202 and 3450:335. The basic techniques employed in control theory, systems analysis, and model identification as they apply to physiological systems.

4800:530. Design of Medical Imaging Systems. (3 Credits)

Prerequisites: 3100:200; 3650:292; 4400:343; 4800:353; 4800:305; or by permission of instructor. Physical principles and engineering design of medical imaging systems, with emphasis on digital radiography, computed tomography, nuclear medicine, ultrasound and magnetic resonance.

4800:560. Experimental Techniques in Biomechanics. (3 Credits)

Prerequisites: 3150:153, 3450:335, 3650:292, 4600:203 or by permission. Principles of testing and measuring devices commonly used for biofluid and biosolid mechanics studies. Laboratories for demonstration and hands-on experience.

4800:570. Human Factors Engineering. (3 Credits)

Reliability and human error, human capabilities and limitations, crew protection, display systems, controls and controlling actions, interface design principles, risk management, Safety and accident prevention.

4800:600. BME Graduate Colloquium. (1 Credit)

(May be repeated for a maximum of 16 credits.) The Biomedical Engineering Colloquium is a seminar series designed to introduce students to current topics in biomedical engineering research, design and business.

4800:601. Biomedical Instrumentation I. (4 Credits)

Prerequisites: 3100:561, 3100:562, and [4400:232 or 4400:320]. Clinical instrumentation to measure and display physiologic and anatomic parameters. Basic concepts of instrumentation including design criteria and operational analysis. Practical experience gained through the use of instrumented mammalian models.

4800:605. Fundamentals of Biomedical Engineering. (4 Credits)

Prerequisites: Graduate Standing in College of Engineering or permission of instructor. This course covers the fundamental areas of biomedical engineering including biomechanics, biomaterials, signal/image processing, biotransport phenomena, controls, and emerging areas.

4800:606. Physiology for Biomedical Science and Engineering. (3 Credits)

An integrative study of the various human body functions with emphasis on cellular, neuromuscular, cardiovascular, and renal physiology and their applications in biomedical engineering.

4800:611. Biometry. (3 Credits)

Statistics and experimental design topics for the biomedical and biomedical engineering disciplines including: distributions, hypothesis testing and estimation, ANOVA, probit analysis and nonparametrics statistics.

4800:620. Neural Networks. (3 Credits)

Examination of highly parallel, distributed architectures for computing that are, to varying degrees, derived from structures observed in biological nervous systems. After an overview of how real neurons operate, the course will examine both lassial and modern neural computing architectures. Comparisons will be made with traditional serial machines and applications for which neural networks seem most promising will be examined.

4800:627. Advances in Drug and Gene Delivery Systems. (3 Credits)

This course will examine technological innovations for the delivery of drugs and genes. Methods of introducing drugs and genes into the body, modeling drug transport, and metabolic responses of cells and organs will be analyzed.

4800:630. Biomedical Computing. (3 Credits)

Prerequisite: 4100:206 or equivalent. Computer applications in health care, clinical laboratories, AMHT, medical records, direct order entry, A-D, D-A conversion, patient monitoring, peripherals and interfaces, diagnostic algorithms, automated EEG, ECG systems.

4800:631. Biomedical Instrumentation I. (4 Credits)

Prerequisites: 4800:605 or permission of the instructor. This course covers biomedical equipment, bio-signals and processing techniques, biomedical sensors/transducers, signal conditioning, data acquisition, noise control, device safety, and modern medical imaging systems.

4800:633. Biomedical Optics. (3 Credits)

Application of lightwave principles and optical fibers on the engineering design and development of instrumentation, techniques, and applications for medical diagnostic imaging, and treatment of disease.

4800:634. Medical Imaging Devices. (3 Credits)

Imagining modalities including radiation, magnetic resonance, and sound. The formation of images. Specific devices including computer tomography, magnetic resonance, ultrasound, gamma cameras and PET.

4800:640. Spine Mechanics. (3 Credits)

Prerequisites: 3100:561 or equivalent; 4300:406 or equivalent; or permission. Physical properties and functional biomechanics of the spine. Kinematics and kinetics of the human spine. Biomechanics of scoliosis, trauma, instability, pain, and orthoses. Mechanics and design of surgical implants.

4800:642. Hard Connective Tissue Biomechanics. (3 Credits)

Prerequisites: 3100:561 or equivalent; 4300:407 or equivalent; or permission. Physical properties and functional biomechanics of bone. The biology and mechanics of fracture and fracture healing. Mechanics of external and internal fixators. Total joint implants and reconstruction techniques.

4800:645. Mechanics in Physiology & Medicine. (3 Credits)

Prerequisites: 4600:310 and 4300:202 or equivalent. Blood rheology, mechanics of microcirculation, finite deformation theory, soft tissue mechanics, mechanics of blood and lymph circulation, kinetics and kinematics of orthopedic joints. Clinical applications.

4800:647. Kinematics of the Human Body. (3 Credits)

Prerequisites: 4600:321 or equivalent, graduate standing in the College of Engineering or by permission. Analytical methods used to model and quantify human body motion. Three-dimensional kinematics, joint coordinate systems, functional anatomy, segment center of mass and joint centers.

4800:650. Cardiovascular Dynamics. (3 Credits)

Analysis of blood pumping action, pressure/flow waveforms and transmission through circulation and blood rheology factors. Use of various modeling and measurement techniques. Clinical implications related to disease.

4800:653. Transport Phenomena in Biology & Medicine. (3 Credits)

Prerequisites: 4200:321 and 4200:322 or 4600:310 and 4600:315 or equivalent. Basic definitions, cardiovascular mass and momentum transport, compartment modeling, mass transfer in physiological systems and artificial kidney and lung devices, Design optimization. Analysis of human thermal system.

4800:654. Microfludics in Biotechnology. (3 Credits)

Prerequisites: 4800:605 or permission of instructor.

4800:655. Rehabilitation Engineering. (3 Credits)

Prerequisites: graduate standing in engineering, mathematics, or science; or permission of the instructor. Devices for rehabilitation, interfacing the motor and/or sensory impaired, quantitative assessment techniques, prosthetics and orthotics, bedsore mechanics, emerging technologies.

4800:660. Biomaterials & Laboratory. (4 Credits)

Corequisite: Biomaterials Laboratory. Material uses in biological applications. Effect of physiological environment and sterilization on materials. Controlled and uncontrolled degradation. Effect of materials on soft tissue, hard tissue and blood. Laboratory experiments using materials designed for biomedical use and demonstrations of biological/materials interactions.

4800:661. Advanced Biomaterials. (3 Credits)

Prerequisite: 4800:660 or permission of instructor. The objective of this course is to provide the fundamental understanding of the host responses when exposed to various implantable devices and biomaterials. Methods for testing biocompatibility will be analyzed.

4800:662. Tissue Engineering & Regenerative Medicine. (3 Credits)

Prerequisites: 4800:661 or permission. This course will cover topics including basic developmental biology, quantitative description of biological processes, and integration of cells with materials to regenerate tissue.

4800:663. Artificial Organs. (3 Credits)

Prerequisites: graduate standing in the College of Engineering or permission of instructor. Study of the rationale for the engineering and clinical aspects required for the design and variety of artificial organs, with emphasis on the artificial heart and artificial kidney.

4800:665. Biomaterials and Tissue Engineering Methods. (3 Credits)

Prerequisite: 4800:660; Corequisite: 4800:661; or permission of the instructor. This course is design to equip students with knowledge and skills to evaluate biomaterials and to design scaffolds for tissue engineering. Analytical techniques include principles of microscopy, cell culture techniques, and biocompatibility testing.

4800:670. Mathematical Modeling in Biology & Medicine. (3 Credits)

Prerequisites: graduate standing in engineering, mathematics, or physics; or permission of instructor. Modeling of pharmacokinetic, cardiovascular, neuromuscular, and immune systems, and artificial organ interactions. Deterministic and stochastic approaches.

4800:685. Medical Devices & Artificial Organs. (3 Credits)

Prerequisites: graduate standing in engineering, mathematics, or science; or permission of instructor. Design of medical devices and artificial organs, requirements, safety considerations, tissue constraints, optimization techniques, government regulations, and legal liability.

4800:697. Special Topics: Biomedical Engineering. (1-4 Credits)

(May be repeated.) Specialized areas of study as defined by the instructor.

4800:698. Masters Research. (1-6 Credits)

Prerequisite: Permission of advisor. (May be repeated.) Research on a suitable topic in biomedical engineering culminating in a master's thesis.

4800:699. Masters Thesis in Biomedical Engineering. (1-6 Credits)

Prerequisite: permission of advisor. (May be repeated) Supervised research in a specific area of biomedical engineering.

4800:898. Preliminary Research. (1-15 Credits)

(May be repeated) Prerequisite: Approval of the dissertation director. Preliminary investigations prior to the submission of a dissertation proposal to the Interdisciplinary Doctoral Committee.

4800:899. Doctoral Dissertation. (1-15 Credits)

Prerequisite: acceptance of research proposal by the Interdisciplinary Doctoral Committee and approval of the dissertation director. (May be repeated) Original research by the doctoral student.